II.2             Biology of the Brain-Mind Identity
A. What is the brain? It is, among other things, an organ that functions as the central control or operating system of the body. Networks of nerve cells , some with fibers a few feet long, run throughout the body and connect all body tissue with the brain. Also, it produces mind or higher thought such as consciousness, self-awareness, thinking about thinking, thinking how we think about thinking, memory, cognition, learning etc., and just like other organs produce digestion, breathing, circulation of the blood, etc. The mind emerged via the brain from the material world of which it is a part. For details of the mind's workings see "Mind and Personality as Mental Traits." It controls all vital activities for survival including sleep, movement, hunger, and thirst. It has many modules or nested structures with no clear demarcation but a blurring of boundaries. The brain's parts seem to work as an imperfectly integrated unit.
    The human brain has the same general structure as the brains of other mammals, but is over five times as large as the "average brain" of a mammal with the same body size. From a philosophical point of view, it might be said that the most important function of the brain is to serve as the physical structure "underlying" the mind. However, from a biological point of view, the most important function is to generate behaviors that promote the welfare of an animal. Brains control behavior either by activating muscles, or by causing secretion of chemicals such as hormones.
B. What is the brain-mind identity?  Some say it is directly analogous, meaning similar in function but not in origin, to the structure and output of the computer hardware-software link or connection. But in reality there is no brain-mind connection because the two are identical. This so far the most plausible description is known as the brain-mind identity theory (also identity theory or physicalism). It holds that mental states are identical to internal states of the brain. In simple but elucidating terms:
A mental state M is nothing other than brain state B. The mental state "desire for a cup of coffee" would thus be nothing more than the "firing of certain neurons in certain brain regions.
One of the first to suggest this theory was the psychologist E. G. Boring (1886-1968) in a book entitled The Physical Dimensions of Consciousness (1933). He wrote that to him:
. . . a perfect correlation is identity. Two events that always occur together at the same time in the same place, without any temporal or spatial differentiation at all, are not two events but the same event.
C. What is the brain's "hardware"? It is by far the most complex structure known to humankind and is still largely unexplored. This miniature universe developed naturally through evolutionary processes that probably started with a few neurons (nerve cells) over 600 million years ago. See "Timeline: Evolution of the Human Brain."
     Concerning the parts and workings of this "hardware":
  • It has roughly 50 to 100 billion (50 or 100 followed by 9 zeros) neurons (nerve cells) that communicate with each other both electrically and chemically (thru more than 50 different neurotransmitters) at their "connections" which are gaps less than a millionth of an inch wide and are named synapses.
  • It secretes a variety of biochemical substances such as the neurotransmitters acetylcholine or norepinephrine that transmit (or inhibit) nerve impulses across a synapse to a postsynaptic element, as another nerve, muscle, or gland. Also, it secretes endorphins that relieve pain and produce feelings of well-being and euphoria. These morphine-like natural opiates are part of the brain's reward system, e.g., for strenuous exercise, falling in love, etc.
  • It has about 100 billion supporting-tissue cells (neuroglia), and other tissues such as the vascular (blood carrying ducts). In adults, the brain consumes about 20 percent of the energy used by the body. This figure is about 60 percent for developing infants.
  • There are about 100 trillion (100 followed by 12 zeros) connections between neurons in adults and young children having about twice as many. This high number is possible because each neuron links to thousands of others. It is this linking of neurons which forms complex circuits (functions, faculties, modules) that allow the various brain parts to connect and function.
  • It has a 100 trillion instructions per second processing capacity. This figure was extrapolated by a researcher, Hans Moravec, from known capabilities of the retina to process image inputs.
D. How can the human brain be understood?  It can be best perceived through its evolutionary development. And the best model is the triune, three brains united, brain  theory advanced by Paul MacLean. Considerable evidence from living fossils, animals that have not changed much over time, and the human brain indicates that three distinct brains emerged successively. The newer brains building on and connecting to the older ones. These three brains are still identifiable in humans . All three now co-inhabit the skull of humans and other animals. Although connected, the three brains, the reptilian brain, the mammalian brain, and the primate brain (neocortex) perform different functions: 
1) The reptilian brain (brainstem) evolved first and connects the spinal cord with the rest of the brain. It allows instinctual and ritualistic behavior such as preening and mating. Together with the spinal cord, it controls the body's vital functions automatically, that is, reflexively without conscious direction. It controls functions such as the muscles of the heart, blood pressure, concentration of salt in the blood, breathing, digestion, body temperature, balance, certain glands, and homeostasis. Where homeostasis refers to the regulation of these functions at a normal level as required for a healthy organism or the internal environment of the body. Reactions such as blushing indicate that regions higher in the brain that involve thinking are also involved in reflexive responses.
2) The mammalian brain (limbic system) unfolded first in mammals. Its main parts are the hippocampus, the amygdala, and the hypothalamus. It strongly influences our behavior thru emotions and instinctive discernments that are triggered when it retrieves pleasant or unpleasant experiences from its storage facility (memory). That is, emotions such as anger, disgust, fear, happiness, hate, love, sadness, shame, and uncertainty. Instinctive discernments are often unconsciously included in our decisions, actions, and value judgments.
3) The primate brain (neocortex) emerged in nonhuman primates and reached its highest development in the human brain with its two large cerebral hemispheres. They facilitate what makes us distinctly human, that is, culture thru voluntary rather than instinctual behavior, language, abstract thought, imagination, and consciousness.
E. Where did neurons (nerve cells) come from? They developed naturally through evolutionary processes that probably started with single-cell organisms where the entire cell surface absorbed stimuli from the environment. In some of these cells there are already discrete light-sensitive structures known as "eyespots." However, the first complete neurons appeared about 600 million years ago in jelly fish.
 
 
(Photo source: Wikimedia Commons)
 
F. How do neurons connect? They do when dendrites of one neuron receive signals from the axons of other neurons thru chemicals known as neurotransmitters of which there are over 50 different kinds. These neurotransmitters set off electrical charges in the dendrites that move the signals electrochemically to the cell body (soma). The cell body integrates the information and transmits it electrochemically down the axon to its tip. As the diagram below shows, these regions of axon to dendrite contact are known as synapses.

G. How do neurons communicate? Although there is a very narrow gap named a synaptic cleft between, they are able to communicate through what is called synaptic transmissions.  As shown in the diagram below, at the tip of of an axon, there are small bubble like structures called synaptic vesicles that release neurotransmitters that carry the signal across the cleft between the axon tip of one neuron and the neurotransmitter receptors at the tip of a dendritic spine of a second neuron.

     To reiterate, the illustration below depicts the major elements in chemical synaptic transmission. An electrochemical wave called an action potential travels along the axon of a neuron. When the wave reaches a synapse, it provokes release of a puff of neurotransmitter molecules, which bind to chemical receptor molecules located in the membrane of another neuron, on the opposite side of the synapse.

File:Chemical synapse schema cropped.jpg

(Picture source: Wikimedia Commons)
 
H. To how many other neurons is an individual one linked?  Each neuron links to thousands of others. Hence, there are roughly 200 trillion (200 followed by 12 zeros) connections in adults and with young children having about twice as many. It is this linking of neurons which forms complex circuits that allow the various brain parts to connect and function. The figure below, by Santiago Ramon y Cajal, illustrates the diversity of neuronal structures in the auditory cortex.

(Image source: Wikimedia Commons)

I. How does the human brain compare to others? The human brain is not the largest one as the comparative pictures below indicate. What apparently counts, however, is brain size relative to body size. Large animals need larger brains not for higher functions such as thinking, but because they have more nerves entering and leaving the brain to their muscles. Fish, amphibians, and reptiles have similar brain sizes, but birds and mammals have much larger brains relative to body size. Also, there are particular parts of the brain that differ. For instance, in humans, the neocortex's two large hemispheres, responsible for high-level brain functions, take up about 85 percent of the brain's weight. 

Picture source: University of Wisconsin and Michigan State Comparative Mammalian Brain Collections and the National Museum of Health and Medicine. In part funded by the National Science Foundation, as well as by the National Institutes of Health. Website: http://en.citizendium.org/wiki/Image:ComparitiveBrainSize.jpg